Interferon Beta-1A: 4 agencies, 2002–2017

This page collects every recorded health technology assessment decision for one molecule across the agencies in our archive, and compares them. The comparison is the point: each agency publishes its own verdict, none publishes how that verdict sits against the others.

What the record shows

No agency in this archive has refused interferon beta-1a: all 5 decisive outcomes across 2 agencies were positive or positive with restrictions.

The file has been open for more than a decade: 15 years separate the first record, 23 Jan 2002 at AWMSG (Wales), from the most recent, 11 Jan 2017 at HAS (France).

No assessment is on file from PBAC (Australia), PHARMAC (New Zealand), CIPM (Spain) and G-BA (Germany), each among the eight highest-volume agencies here.

Not every gap is a refusal: for interferon beta-1a, 1 submission was never made — an outcome set by the company rather than the assessor.

Nothing has been added since 2017; on this evidence the file is dormant.

3 distinct indication wordings are recorded for interferon beta-1a by the agencies that label one in English (AWMSG and SMC).

AWMSG (Wales) was first to assess interferon beta-1a, on 23 Jan 2002; SMC (Scotland) did not open a file until 12 Nov 2012 — an unusually long tail of 10.8 years between the earliest and latest system to look at it.

The record arrives in waves: 4 separate years each carry two or more decisions, spread across 9 years in total.

3 of the 4 agencies here assessed interferon beta-1a more than once, HAS (France) most often at 9 entries — repeat review is the norm for this molecule rather than the exception.

Coverage is narrow: only 4 of the 18 agencies here have assessed interferon beta-1a.

The full ledger for interferon beta-1a reads 7 other, 5 recommended, 1 non-submission and 1 superseded, with 1 in other categories.

Decisions on file

AgencyDateIndication as recorded OutcomeSource
HAS (France)11 Jan 2017Listing renewal (Transparency Committee)SMR substantialsource
HAS (France)5 Oct 2016Listing renewal (Transparency Committee)SMR substantialsource
SMC (Scotland)12 Nov 2012Patients with a single demyelinating event with an active inflammatory process, if alternative diagnoses have been excluded, and if they are determined to be at high risk…not recommendedsource
AWMSG (Wales)19 Jun 2012Treatment of patients with a single demyelinating event with an active inflammatory processsuperseded (non-submission)source
TLV (Sweden)12 Oct 2011Ny form av Avonex, AvonexPen, ingår i högkostnadsskyddetgeneral subsidysource

10 further decisions for interferon beta-1a, across 3 agencies, are not shown here. They link to 8 further source documents.

Related molecules

Coverage: 15 decisions for interferon beta-1a from 4 agencies, 2002 to 2017. Data to 7 Sep 2026. ATC class L03A — Immunostimulants. How this page is produced. Compiled by Altima Partners; queries: sales@altimapartners.co.uk.

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