Propranolol: where the agencies disagree

This page collects every recorded health technology assessment decision for one molecule across the agencies in our archive, and compares them. The comparison is the point: each agency publishes its own verdict, none publishes how that verdict sits against the others.

What the record shows

G-BA (Germany), HAS (France) and PBAC (Australia), among others, recommended or restricted propranolol, while AWMSG (Wales) did not recommend it.

The file has been open for more than a decade: 12.6 years separate the first record, 5 Dec 2007 at HAS (France), from the most recent, 9 Jul 2020 at HAS (France).

No assessment is on file from SMC (Scotland) and CIPM (Spain), each among the eight highest-volume agencies here.

Nothing has been added since 2020; on this evidence the file is dormant.

2 of these 14 records carry a year of decision but no day, so any interval quoted here is approximate to within a year.

HAS (France) was first to assess propranolol, on 5 Dec 2007; PBAC (Australia) did not open a file until 2015 — a wide spread of 7.6 years between the earliest and latest system to look at it.

The record arrives in waves: 3 separate years each carry two or more decisions, spread across 8 years in total.

3 of the 6 agencies here assessed propranolol more than once, HAS (France) most often at 6 entries — repeat review is the norm for this molecule rather than the exception.

6 of the 18 agencies in this archive hold a record for propranolol.

The full ledger for propranolol reads 10 recommended, 2 other, 1 not recommended and 1 advice.

Decisions on file

AgencyDateIndication as recorded OutcomeSource
HAS (France)9 Jul 2020Listing renewal (Transparency Committee)SMR substantial · ASMR IIIsource
PBAC (Australia)2015Infantile hemangiomaThe PBAC rejected the proposed price for Hemangiol and reaffirmed its decision in March 20…source
TLV (Sweden)20 Feb 2015Hemangiol ingår i högkostnadsskyddetgeneral subsidysource
G-BA (Germany)19 Feb 2015Hemangiol — benefit assessment §35aadded benefit: major (indication)source
AWMSG (Wales)14 Aug 2014for the treatment of proliferating infantile haemangioma requiring systemic therapy: life- or function-threatening haema…not endorsed (non-submission)source

9 further decisions for propranolol, across 4 agencies, are not shown here. They link to 7 further source documents.

Related molecules

Coverage: 14 decisions for propranolol from 6 agencies, 2007 to 2020. Data to 7 Sep 2026. ATC class C07A — Beta blockers. How this page is produced. Compiled by Altima Partners; queries: sales@altimapartners.co.uk.

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