Triptorelin: 4 agencies, 2005–2021

This page collects every recorded health technology assessment decision for one molecule across the agencies in our archive, and compares them. The comparison is the point: each agency publishes its own verdict, none publishes how that verdict sits against the others.

What the record shows

The file has been open for more than a decade: 16.2 years separate the first record, 9 May 2005 at SMC (Scotland), from the most recent, 2021 at PBAC (Australia).

HAS (France) changed its position: recommended on 15 Oct 2014, not recommended by 19 Sep 2018.

No assessment is on file from PHARMAC (New Zealand), TLV (Sweden), CIPM (Spain) and G-BA (Germany), each among the eight highest-volume agencies here.

Not every gap is a refusal: for triptorelin, 1 submission was never made — an outcome set by the company rather than the assessor.

Nothing has been added since 2021; on this evidence the file is dormant.

The programme is broad: 8 distinct indication wordings are recorded for triptorelin by the agencies that label one in English (AWMSG, PBAC and SMC).

2 of these 17 records carry a year of decision but no day, so any interval quoted here is approximate to within a year.

SMC (Scotland) was first to assess triptorelin, on 9 May 2005; PBAC (Australia) did not open a file until 2016 — an unusually long tail of 11.2 years between the earliest and latest system to look at it.

The record arrives in waves: 4 separate years each carry two or more decisions, spread across 13 years in total.

4 of the 4 agencies here assessed triptorelin more than once, HAS (France) most often at 8 entries — repeat review is the norm for this molecule rather than the exception.

Coverage is narrow: only 4 of the 18 agencies here have assessed triptorelin.

The full ledger for triptorelin reads 9 recommended, 4 other, 2 not recommended and 1 non-submission, with 1 in other categories.

Decisions on file

AgencyDateIndication as recorded OutcomeSource
PBAC (Australia)2021Central precocious puberty (CPP)Recommendedsource
SMC (Scotland)7 Oct 2019Triptorelin (Decapeptyl SR 3 mg), a gonadotropin-releasing-hormone (GnRH) agonist, is indicated as adjuvant treatment, in combination with tamoxifen or an aromatase inhib…acceptedsource
HAS (France)19 Sep 2018Indication extensionSMR insufficientsource
SMC (Scotland)11 Jun 2012Reversible reduction of testosterone to castrate levels in order to decrease sexual drive in adult men with severe sexual deviations.not recommendedsource
AWMSG (Wales)6 Jun 2011Treatment of patients with locally advanced, non-metastatic prostate cancer, as an alternative to surgical castration. T…outside AWMSG criteriasource

12 further decisions for triptorelin, across 4 agencies, are not shown here. They link to 8 further source documents.

Related molecules

Coverage: 17 decisions for triptorelin from 4 agencies, 2005 to 2021. Data to 7 Sep 2026. ATC class L02A — Endocrine therapy. How this page is produced. Compiled by Altima Partners; queries: sales@altimapartners.co.uk.

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