Vericiguat: where the agencies disagree

This page collects every recorded health technology assessment decision for one molecule across the agencies in our archive, and compares them. The comparison is the point: each agency publishes its own verdict, none publishes how that verdict sits against the others.

What the record shows

CHUIKYO (Japan) and G-BA (Germany) recommended or restricted vericiguat, while ZIN (Netherlands) did not recommend it.

Every record falls within a 1.9-year window, 24 Jun 2021 to 12 May 2023 — a compressed review cycle.

TLV (Sweden) changed its position: not recommended on 11 Apr 2022, restricted by 29 Mar 2023, after a resubmission.

No assessment is on file from HAS (France), PHARMAC (New Zealand) and CIPM (Spain), each among the eight highest-volume agencies here.

Not every gap is a refusal: for vericiguat, 1 submission was never made and 1 was withdrawn or terminated before a decision — an outcome set by the company rather than the assessor.

4 distinct indication wordings are recorded for vericiguat by the agencies that label one in English (AWMSG, NICE, PBAC and SMC).

2 of these 12 records carry a year of decision but no day, so any interval quoted here is approximate to within a year.

AWMSG (Wales) was first to assess vericiguat, on 24 Jun 2021; PBAC (Australia) did not open a file until 2022 — a moderate spread of 1.1 years between the earliest and latest system to look at it.

Activity is concentrated rather than steady: 5 of 12 dated records fall in 2021 alone.

4 of the 8 agencies here assessed vericiguat more than once, ZIN (Netherlands) most often at 2 entries — repeat review is the norm for this molecule rather than the exception.

8 of the 18 agencies in this archive hold a record for vericiguat.

The full ledger for vericiguat reads 3 not recommended, 3 recommended, 1 advice and 1 restricted, with 4 in other categories.

Decisions on file

AgencyDateIndication as recorded OutcomeSource
ZIN (Netherlands)12 May 2023GVS-advies herbeoordeling vericiguat (Verquvo®) voor de behandeling van volwassenen met chronisch hartfalenadvice published (GVS)source
TLV (Sweden)29 Mar 2023Verquvo ingår i högkostnadsskyddet med begränsning.restricted subsidysource
PBAC (Australia)2022Chronic heart failureRecommendedsource
G-BA (Germany)3 Mar 2022Verquvo — benefit assessment §35aadded benefit: minor (hint)source
SMC (Scotland)11 Oct 2021For treatment of symptomatic chronic heart failure in adult patients with reduced ejection fraction who are stabilised after a recent decompensation event requiring IV th…not recommendedsource

7 further decisions for vericiguat, across 6 agencies, are not shown here. They link to 6 further source documents.

Related molecules

Coverage: 12 decisions for vericiguat from 8 agencies, 2021 to 2023. Data to 7 Sep 2026. ATC class C01 — Cardiac therapy. How this page is produced. Compiled by Altima Partners; queries: sales@altimapartners.co.uk.

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