TLV: molecules with a published decision record
323 molecules on this site carry at least one TLV decision. Each page compares that decision with every other agency that assessed the same molecule.
| Molecule | Decisions | Agencies | Class |
|---|---|---|---|
| adalimumab | 133 | 11 | Immunosuppressants |
| dupilumab | 116 | 15 | Other dermatologicals |
| daratumumab | 115 | 15 | Antineoplastics |
| olaparib | 114 | 15 | Antineoplastics |
| ibrutinib | 108 | 15 | Antineoplastics |
| upadacitinib | 93 | 16 | Immunosuppressants |
| secukinumab | 79 | 12 | Immunosuppressants |
| budesonide | 76 | 12 | Antidiarrheals / intestinal anti-inflammatories |
| tocilizumab | 76 | 12 | Immunosuppressants |
| ustekinumab | 71 | 11 | Immunosuppressants |
| infliximab | 69 | 9 | Immunosuppressants |
| lenalidomide | 68 | 13 | Immunosuppressants |
| denosumab | 67 | 11 | Bone diseases |
| etanercept | 67 | 8 | Immunosuppressants |
| osimertinib | 65 | 14 | Antineoplastics |
| dapagliflozin | 64 | 12 | Diabetes |
| empagliflozin | 64 | 13 | Diabetes |
| everolimus | 61 | 9 | Antineoplastics |
| venetoclax | 61 | 14 | Antineoplastics |
| tofacitinib | 60 | 13 | Immunosuppressants |
| mepolizumab | 59 | 15 | Obstructive airway diseases |
| glucose | 58 | 7 | Blood substitutes and perfusion |
| zanubrutinib | 58 | 16 | Antineoplastics |
| cabozantinib | 56 | 15 | Antineoplastics |
| guselkumab | 56 | 13 | Immunosuppressants |
| risankizumab | 56 | 14 | Immunosuppressants |
| bimekizumab | 55 | 14 | Immunosuppressants |
| rivaroxaban | 55 | 11 | Antithrombotics |
| brentuximab vedotin | 54 | 12 | Antineoplastics |
| selpercatinib | 53 | 13 | Antineoplastics |
| semaglutide | 53 | 14 | Diabetes |
| acalabrutinib | 52 | 14 | Antineoplastics |
| enzalutamide | 52 | 12 | Endocrine therapy |
| somatropin | 51 | 9 | Pituitary and hypothalamic hormones |
| ribociclib | 50 | 14 | Antineoplastics |
| ruxolitinib | 50 | 12 | Antineoplastics |
| lenvatinib | 49 | 14 | Antineoplastics |
| nintedanib | 49 | 15 | Antineoplastics |
| baricitinib | 48 | 14 | Immunosuppressants |
| abemaciclib | 47 | 15 | Antineoplastics |
| vedolizumab | 44 | 12 | Immunosuppressants |
| certolizumab pegol | 43 | 11 | Immunosuppressants |
| golimumab | 43 | 10 | Immunosuppressants |
| omalizumab | 43 | 12 | Obstructive airway diseases |
| niraparib | 42 | 15 | Antineoplastics |
| aripiprazole | 41 | 8 | Psycholeptics |
| ixekizumab | 41 | 11 | Immunosuppressants |
| ranibizumab | 41 | 10 | Ophthalmologicals |
| evolocumab | 39 | 11 | Lipid modifying agents |
| dabrafenib | 38 | 14 | Antineoplastics |
| darolutamide | 38 | 15 | Endocrine therapy |
| elexacaftor / ivacaftor / tezacaftor | 38 | 9 | Other respiratory |
| methotrexate | 38 | 5 | Immunosuppressants |
| alectinib | 37 | 15 | Antineoplastics |
| alirocumab | 37 | 13 | Lipid modifying agents |
| buprenorphine | 36 | 7 | Other nervous system |
| cannabidiol | 35 | 12 | Antiepileptics |
| crizotinib | 35 | 12 | Antineoplastics |
| emicizumab | 35 | 12 | Antihemorrhagics |
| melatonin | 35 | 8 | Psycholeptics |
| abatacept | 34 | 10 | Immunosuppressants |
| dexamethasone | 34 | 8 | Ophthalmologicals |
| tacrolimus | 34 | 8 | Immunosuppressants |
| levetiracetam | 33 | 6 | Antiepileptics |
| natalizumab | 33 | 12 | Immunosuppressants |
| pegcetacoplan | 33 | 16 | Ophthalmologicals |
| hydrocortisone | 32 | 10 | Systemic corticosteroids |
| metformin / sitagliptin | 32 | 6 | Diabetes |
| apixaban | 31 | 11 | Antithrombotics |
| benralizumab | 31 | 15 | Obstructive airway diseases |
| bortezomib | 31 | 7 | Antineoplastics |
| fluticasone | 31 | 8 | Nasal preparations |
| liraglutide | 31 | 9 | Diabetes |
| avapritinib | 30 | 11 | Antineoplastics |
| entrectinib | 30 | 13 | Antineoplastics |
| fingolimod | 30 | 12 | Immunosuppressants |
| idelalisib | 30 | 8 | Antineoplastics |
| midazolam | 30 | 9 | Psycholeptics |
| regorafenib | 30 | 12 | Antineoplastics |
| larotrectinib | 29 | 14 | Antineoplastics |
| palbociclib | 29 | 13 | Antineoplastics |
| sitagliptin | 29 | 7 | Diabetes |
| sofosbuvir | 29 | 11 | Antivirals |
| apalutamide | 28 | 12 | Endocrine therapy |
| apremilast | 28 | 10 | Immunosuppressants |
| belimumab | 28 | 12 | Immunosuppressants |
| letermovir | 28 | 14 | Antivirals |
| tafamidis | 28 | 16 | Other nervous system |
| abiraterone | 27 | 10 | Endocrine therapy |
| dasatinib | 27 | 8 | Antineoplastics |
| enoxaparin | 27 | 6 | Antithrombotics |
| filgrastim | 27 | 6 | Immunostimulants |
| tadalafil | 27 | 7 | Urologicals |
| teriparatide | 27 | 8 | Calcium homeostasis |
| vutrisiran | 27 | 15 | Other nervous system |
| cladribine | 26 | 12 | Immunosuppressants |
| fenfluramine | 26 | 14 | Antiepileptics |
| filgotinib | 26 | 13 | Immunosuppressants |
| insulin glargine | 26 | 6 | Diabetes |
| lorlatinib | 26 | 12 | Antineoplastics |